Whole Exome Sequencing (WES) Service

Exome sequencing is a technique for sequencing all the protein-coding genes in a genome (known as the exome). It consists of first selecting only the subset of DNA that encodes proteins (known as exons) and then sequencing that DNA using any high-throughput DNA sequencing technology. Quick Biology is a professional Whole Exome Seq (WES) service provider.   

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Quick Biology WES Data Analysis Workflow:



Sample requirements:

• DNA amount quantified by Nanodrop:  ≥500 ng for normal input; minimum 20 ng

• DNA concentration: ≥2 ng/μL

• Total volume: ≥10 μL

• Purity: OD260/280= 1.8-2.0 without degradation or RNA contamination

Bioinformatics service for WES:

        a.Germline variants, compared to reference genome

        b.Somatic mutations if Tumor-Normal pair (SNVs, InDel, CNV)

Turnaround time:

About 3-4 weeks, depends on the quality of submitted samples